A remote controlled drug delivery capsule for use in absorption studies has been developed by a UK company. The new technology, called the Enterion capsule. The Enterion capsule has been developed to investigate the absorption of The technology has been in routine use for several years and. formulations and delivery technologies that target the right place in the GI tract. delivered to specific sites via the Enterion capsule. The drugs.

Author: Zulugami Nejas
Country: Canada
Language: English (Spanish)
Genre: Marketing
Published (Last): 17 May 2004
Pages: 20
PDF File Size: 19.35 Mb
ePub File Size: 14.14 Mb
ISBN: 725-4-98404-199-1
Downloads: 39064
Price: Free* [*Free Regsitration Required]
Uploader: Zologis

Formulation tech goes Enterion

Capskle endoscopy in This provides an extra degree of freedom that enables various advanced functions such as axial position control, drug releasing, drug injection, or biopsy. Advantages of the rolling ability include smooth and continuous locomotion and stable steering because the capsule is always technklogy to the tissue surface while moving, it allows improved tissue surface diagnosis and tissue targeting capability for therapeutic procedures, and it provides a more complete view of the 3-D stomach tissue wall; thus reducing the possibility of missing problematic tissue areas of the stomach wall.

Latest views Mark Lyonette: The capsule is activated by a radiofrequency signal, which releases a spring-controlled piston and leads technollogy release of the capsule contents see Figure.

In this section, the multimodal drug release is simulated in detail. Docking is based on permanent magnets for energy efficiency purposes.

Next, the chamber has four slits at its corners, which are toward the space between side linkages. A large volume of the drug is released and the area around the target is coated by the released drug.


The distance h between the external magnet and the capsule was measured. Swallowable medical devices for diagnosis and surgery: The full spectrum of the commercial capsule models is available elsewhere and remains beyond the scope of this editorial[ 812 ]. To date, the proposed devices consist of modules for the complete process of biopsy, which includes monitoring the intestinal wall by a tissue monitoring module, aligning onto a polyp by an anchor, and sampling of the polyp tissue by a biopsy module.

For example, in the case of the M 4about mm 2 is capsue by the polymeric drug, and the average distance is about 8 mm. Eur J Pharm Sci. It is a remote-controlled device that is capable of precisely delivering pharmaceutically relevant drug formulations both liquids and solids to specific sites within the GI tract.

As a result, a viscous polymeric coating is formed around the target. Disease Management covers the diseases commonly encountered entrrion primary care by system, with common therapeutic issues. Intestinal biomechanics simulator for robotic capsule endoscope validation.

Remote control capsule for absorption studies. The white dotted line means the area of the drug chamber.

The first generation, radiation-free pill MTS-1capsue been introduced for description of gastrointestinal motility in adults. Data from each sensor with an iterative algorithm are used to calculate the position and orientation of the magnetic pill[ 6263 ].

We provide tailored solutions for pharmaceutical, biotechnology and agrochemical tecchnology, using state-of-the-art technologies underpinned by unparalleled medical, chemical and biological expertise. Disease Management Disease Cspsule covers the diseases commonly encountered in primary care by system, with common therapeutic issues.


However, no human studies have been conducted with this capsule, which has been described on the web for almost a decade now[ 12 ]. The authors would like to thank H. This editorial presents current commercially-available new designs, European projects and delivery capsule and gives an overview of the progress required and progress that will be achieved -according to the opinion of the authors- in the next 5 year leading enterionn The second section is from the point A to the point B.

December 24, Peer-review started: A consortium funded by EU 6 th Framework Programme FP duringworked on NEMO Nano based capsule-Endoscopy with Molecular Imaging technolofy Optical biopsy project[ 44 ] with main aim to develop an advance cancer screening method friendly enough to significantly increase compliance, simplify the diagnostic pathway and increase the sensitivity and specificity of early detection[ 3545 ].

Expert Rev Gastroenterol Hepatol. One possible solution for the first issue is to assemble the drug chamber with the main capsule in the stomach after inserting separately.

There was a problem providing the content you requested

Mosaicing is a process by which the final image on the computer display is made by tecgnology multiple images taken from various angles[ 2325 ].

The consortium aimed to merge few technological platforms: In this case, the gradient of the plot between the point O and the point A [see Fig. New vision in video capsule endoscopy: